In this paper, we propose a mathematical and computational model for the GBM initiating of recurring focus as a quasi-spherical absorbing receiver considering the irregular shape as a Bernoulli trial process that accounts for the uncontrollable tumor growth over an initial spherical surface. Our results show that when GBM grow to irregular quasi-sphere shapes, they will increase the channel capacity, which is fully aligned with the evolution and configuration of GSC niches in GBM cultures.